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Scientist 3, Immunology and Ophthalmology, Sudharsan LabRoche · South San Francisco
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Scientist 3, Immunology and Ophthalmology, Sudharsan Lab

🗓️ Posted 2026-09-29 South San Francisco Full-time Hybrid Science Technology
💰 Salary Not shared 📊 Market 10,000 CHF–14,000 CHF/mo

About the Company

Roche is a global pioneer in pharmaceuticals and diagnostics focused on advancing science to improve people's lives. The combined strengths of pharmaceuticals and diagnostics under one roof have made Roche the leader in personalised healthcare - a strategy that aims to fit the right treatment to each patient in the best way possible. Roche is the world's largest biotech company, with truly differentiated medicines in oncology, immunology, infectious diseases, ophthalmology and diseases of the central nervous system. Roche is also the world leader in in vitro diagnostics and tissue-based cancer diagnostics, and a frontrunner in diabetes management. Founded in 1896, Roche continues to search for better ways to prevent, diagnose and treat diseases and make a sustainable contribution to society. The company also aims to improve patient access to medical innovations by working with all relevant stakeholders. Thirty medicines developed by Roche are included in the World Health Organization Model Lists of Essential Medicines, among them life-saving antibiotics, antimalarials and cancer medicines. Roche has been recognised as the Group Leader in sustainability within the Pharmaceuticals, Biotechnology & Life Sciences Industry ten years in a row by the Dow Jones Sustainability Indices (DJSI). For more information, please visit https://careers.roche.com Read our community guidelines here: https://www.roche.com/some-guidelines.htm Roche Biotechnology Pharmaceuticals Diagnostics Healthcare PersonalisedHealthcare GreatPlaceToWork Innovation Biotechnology Research Specialties: biotechnology, innovation, personalized healthcare, great place to work, diagnostics, pharmaceuticals, research, healthcare, personalised healthcare, diabetes care, genomics, healthcare technology, big data, Science

About the Role

The Sudharsan Lab in the Department of Immunology and Ophthalmology at Genentech is seeking a highly motivated, resilient, and curious Scientist 3 to drive the target identification, validation, and development of novel therapies for retinal diseases, with a strong focus on Age-Related Macular Degeneration (AMD). As part of Genentech Research and Early Development (gRED), scientists bridge basic biology and translational drug discovery. In this role, you will design and execute research strategies using advanced retinal cellular systems to validate targets, elucidate disease mechanisms, and advance novel therapies. You will collaborate closely with multidisciplinary teams to translate biological insights into therapeutic candidates and share your findings at internal forums and external conferences.

Responsibilities

  • ● Develop human iPSC-derived retinal models (such as RPE and photoreceptors) and design cell-based assays to validate novel targets, study AMD pathogenesis, and evaluate therapeutic candidates.
  • ● Quickly learn and implement new experimental workflows and analytical tools as project priorities evolve.
  • ● Maintain rigorous experimental design, meticulous electronic lab records, and high standards of data reproducibility.
  • ● Collaborate effectively with interdisciplinary teams across the department and broader gRED functional areas.
  • ● Communicate research findings clearly across internal project teams and at external scientific conferences.

Requirements

  • ● Ph.D. in Stem Cell Biology, Neuroscience, Cell Biology, Developmental Biology, Ophthalmology, or a closely related scientific discipline.
  • ● Strong background in cell culture-based assay development, execution, and troubleshooting.
  • ● A strong track record of peer-reviewed publications in reputable scientific journals.
  • ● Excellent interpersonal and collaborative skills with a proven ability to work effectively within large, cross-functional group settings.
  • ● A strong desire and enthusiasm to learn and integrate new experimental techniques, assays, and analytical tools.
  • ● Direct research experience in retinal cell biology, ocular tissue models, or specialized research in Age-Related Macular Degeneration (AMD) or inherited retinal degenerations.
  • ● Familiarity with target engagement assays, high-throughput screening, or translational pipeline workflows.
  • ● Relocation benefits are available for this job posting.
  • ● The expected salary range for this position based on the primary location of South San Francisco, CA is 103,400 to 192,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

  • ● Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
  • ● If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants .