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Senior Principal Scientist (Thereputic Translation)Cancer Research UK (CRUK) · CRT Cambridge Lab
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Cancer Research UK (CRUK)

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Senior Principal Scientist (Thereputic Translation)

🗓️ Posted 2026-09-25 CRT Cambridge Lab Hybrid Science Technology
💰 Salary 4,867 GBP–6,333 GBP/mo (58,400 GBP–76,000 GBP/yr) 📊 Market 6,000 GBP–8,500 GBP/mo

About the Company

We're the world's largest charity dedicated to saving lives through research. Cancer Research UK is the world's leading cancer charity dedicated to saving lives through research, influence and information. Nearly one in two of us will get cancer in our lifetime, but we're finding new ways to outsmart it, so that more people can live longer, better lives free from the fear of cancer. We carry out scientific research to help prevent, diagnose and treat cancer and our groundbreaking work, funded almost entirely by the general public, will ensure that millions more people survive. Together we are beating cancer. Registered charity No. 1089464. Non-profit Organizations Specialties: cancer research, fundraising, volunteering, charity events

Responsibilities

  • ● Senior Principal Scientist (Therapeutic Translation)
  • ● 58,400 - 76,000 plus benefits
  • ● Department: Therapeutic Innovation - R&I
  • ● Reports to: Chief Scientific Officer
  • ● Contract type/hours: Permanent, Full-time 35 hours per week (flexible working requests will be considered).
  • ● Closing date: Sunday 18th October 23:55pm
  • ● Interview Date: To be confirmed.
  • ● Interview process: Competency-based interview process with task/presentation.
  • ● At Cancer Research UK, we exist to beat cancer.
  • ● At Cancer Research Horizons (CRH) our Therapeutic Innovation team is investing in a world leading capability to translate breakthrough discovery science into the next generation of oncology therapeutics. As part of this evolution, we have established a new Therapeutic Translation team. A group of experienced oncology drug discoverers dedicated to identifying, shaping, and accelerating the most exciting science emerging from the CRUK research ecosystem. Every role at CRH is united by a single mission: beating cancer sooner. We carry out work that matters - impacting patients, families, and the future of science.
  • ● As a Senior Principal Scientist, you will play a pivotal role in evaluating the breadth of CRUK's research portfolio, as well as emerging scientific areas with strong therapeutic potential. Working across CRUK Institutes, Centres, and international academic collaborations, you will build trusted relationships with scientific leaders to uncover early stage ideas with the potential to become validated, fundable therapeutic concepts.
  • ● This is an outward facing, high visibility role that requires deep scientific insight, strategic judgement, and a natural curiosity for uncovering translational opportunity before it becomes obvious. You will help transform breakthrough biology into new medicines for cancer patients, shaping not only individual projects, but the future direction of CRUK funded oncology research itself.
  • ● This position offers a rare opportunity for an accomplished drug hunter to influence therapeutic innovation on a national scale and support the discovery of tomorrow's cancer therapies. You'll be joining over 200 staff across CRH from both industrial and academic backgrounds, all dedicated to bringing forward the day we cure cancer.
  • ● What will you be doing
  • ● Support the implementation of a new Therapeutic Translation strategy for CRH TI to enhance the number of therapeutic opportunities identified from CRUK funded research.
  • ● Maintain awareness of emerging areas of cancer biology and technological advances relevant to the objectives of CRH TI in order to identify and recommend priority translational opportunities for examination or investment.
  • ● Analyse current and future CRUK funded research to highlight key translational opportunities.
  • ● Work with CRUK PIs, Research Institutes and Centres, within the UK and internationally (CRUK/NCI Grand Challenges or Academic Alliances) to identify translational opportunities.
  • ● Perform detailed reviews of opportunities identified.