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Director, Cancer Vaccine Preclinical StrategyAstraZeneca · US – Boston International Place – MA
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AstraZeneca

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Director, Cancer Vaccine Preclinical Strategy

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🗓️ Posted 2026-09-29 US – Boston International Place – MA Full-time Hybrid Science Technology
💰 Salary 14,625 GBP–21,937 GBP/mo (175,498 GBP–263,248 GBP/yr) 📊 Market 12,500 GBP–18,333 GBP/mo

About the Company

The Director of Cancer Vaccine Preclinical Strategy is responsible for leading efforts to develop and deliver a portfolio of the new modalities to train the immune system to recognize and eliminate malignant cells. The Director will build on previous experience in cancer vaccines to exploit various vaccine platforms to drive long-lived, robust immune responses to prevent, treat, and drive long-lived surveillance of tumors. Building on the current state of the field, the Director will be tasked with developing preclinical strategy, guiding antigen discovery, supporting vaccine design, and developing combinatorial approaches to amplify clinical impact. The candidate will lead work across cross-functional teams to build programs. The Director will be responsible for driving collaboration and influencing internal stakeholders. In addition, the Director will develop and build a cutting-edge portfolio of intellectual property- guiding a team that fosters high-performance and innovation; building capabilities across immunology, oncology, and translational sciences; and establishing clear operating mechanisms to accelerate decision-making and delivery. Accountabilities Develop a preclinical pipeline for the design, testing, and delivery of cancer vaccine programs Implement a strategy to explore multiple vaccine modalities to train immunity to eliminate tumors Create an approach to evaluate combinatorial modalities to maximize control, clearance, and sur

Requirements

  • ● PhD or equivalent in immunology, oncology, molecular biology, biochemistry or a related discipline with 10+ yrs industry experience
  • ● Proven experience developing novel immunological approaches to deploy immunity to fight tumors
  • ● Proven experience with immune profiling, tumor modelling, systems biology, and/or immune oncology
  • ● Experience working in a cross-functional team to maximize expertise and accelerate success
  • ● Experience developing and implementing novel methods to support vaccine development
  • ● Experience supporting or leading interdisciplinary vaccine discovery or development programs
  • ● Proven experience leading and managing junior colleagues
  • ● Proven experience developing and controlling budgets
  • ● Excellent written and verbal communication, business analysis, and consultancy skills
  • ● The annual base pay for this position ranges from 175,498.40 - 263,247.60 USD. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program 401(k) plan ; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
  • ● Date Posted 29-Sept-2026
  • ● Closing Date 12-Oct-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.