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AstraZeneca

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Senior Global Medical Affairs Lead CVRM

🗓️ Posted 2026-08-21 US - Gaithersburg - MD Full-time Hybrid Healthcare Medical

Company shared salary

20,297 GBP–30,448 GBP/mo (243,569 GBP–365,379 GBP/yr)

Market rate

15,000 GBP–25,000 GBP/mo (180,000 GBP–300,000 GBP/yr)

Based on similar roles (title + domain + location).

About the Company

Job is based either in Gaithersburg, MD or Boston, MA and requires to be in the office 3 days a week. Role Summary: Reporting to the Medical Head the Senior Global Medial Affairs Lead Cardiovascular is a highly experienced Medical Affairs leader with proven vision and impact. This individual develops and leads bold medical strategies within the CVRM therapy area, expertly guiding cross-functional and cross-regional teams to deliver and exceed ambitious goals. The Senior GMAL's influence is enterprise-wide-shaping global medical agendas through Global Medical Team, Global Product Team, and Disease Area Team leadership, and deep partnership with Medical and Commercial functions in markets and regions worldwide. This role demands a leader who champions innovative, disruptive thinking-identifies and shapes breakthrough opportunities, reimagines market dynamics, and accelerates high-impact evidence generation and medical change initiatives. The Senior GMAL navigates and transforms health systems, leverages digital and advanced analytics, drives stakeholder engagement, and ensures AstraZeneca's science leads externally and internally through world-class medical evidence and strategic partnerships. Expectations of a Senior GMAL include: Strategy & Transformation: The Senior GMAL designs and leads the implementation of product and disease area strategies, as well as ambitious practice change initiatives, at a global level. This requires a deep understanding of healthcare

Requirements

  • Minimum of Master's degree or higher with at least 5 years of experience in the pharmaceutical industry (Medical, Marketing, R&D, Market Access), or extensive experience within a health system (clinical, pharmacy, pathway design, etc.).
  • Demonstrated leadership in complex, global healthcare environments, including leading franchise/TA business in key markets, driving brand performance, and managing large, diverse teams including global launch of major products.
  • Significant expertise and strategic insight into healthcare system pathways, regulatory landscapes, market-shaping, and external stakeholder engagement.
  • Strong track record of internal and external network building, collaboration across geographies and matrix teams, and effective mentoring of junior colleagues or peers.
  • Digital proficiency, leveraging digital health tools and data platforms to advance evidence generation and communication.
  • Deep understanding of patient care pathways, evolving treatment protocols, scientific literature, and contemporary approaches to healthcare transformation.
  • Proven ability to guide, influence, and align diverse stakeholders-including thought leaders, regulatory bodies, patient groups, and payer organisations.
  • Doctoral-level degree (MD, PhD, PharmD) in a relevant discipline.
  • Recognized expertise in the relevant or related therapeutic area, often evidenced by a history of clinical practice, research leadership, or significant external engagement.
  • Advanced experience designing, leading, and interpreting clinical research programs, including pivotal clinical trials (Ph2-Ph4), practice-changing RWE studies, and implementation of innovative evidence generation approaches.
  • Broad experience beyond Medical Affairs; for example, prior roles in Marketing, R&D, or Market Access.
  • Long-standing relationships with global KOLs, societies, regulators, digital health partners, and innovative healthcare organisations.
  • Track record of launching new products or indications in multiple, diverse markets (e.g., US, China, EU), and successfully developing and executing global medical strategies.
  • The annual base pay for this position ranges from 243,569 - 365,379 . Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program 401(k) plan ; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
  • Date Posted 21-Aug-2026
  • Closing Date 24-Sep-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.