search Browse Jobs
Thesis Work, 30 Credits - Development of Virus-Like Particles (VLPs) for Non-Hepatic Delivery of CRISPR ReagentsAstraZeneca · Sweden - Gothenburg
AstraZeneca logo

AstraZeneca

company page ↗ Visa Sponsoring Company

Thesis Work, 30 Credits - Development of Virus-Like Particles (VLPs) for Non-Hepatic Delivery of CRISPR Reagents

✓ This company has sponsored visas before. The posting doesn't say so, but it's still worth applying.

🗓️ Posted 2026-10-03 Sweden - Gothenburg Full-time Hybrid Science Technology
💰 Salary Not shared 📊 Market 15,000 GBP–25,000 GBP/mo

About the Company

o feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.

Responsibilities

  • ● The project will focus on the following primary objectives:
  • ● Explore and evaluate novel capsid proteins that can redirect VLP delivery from the liver to tissues of interest.
  • ● Establish and standardize reproducible protocols for VLP assembly, purification, and CRISPR cargo packaging.
  • ● Develop quality control readouts covering particle concentration, size distribution, cargo loading, and functional integrity.
  • ● Evaluate the delivery efficiency and editing activity of selected VLP candidates in relevant cell-based models.
  • ● Analyze and interpret experimental data, document results rigorously, and communicate findings through scientific presentations and written reporting.
  • ● As a stretch objective, and depending on the progress of the project and your interests, you may also have the opportunity to evaluate lead candidates in appropriate mouse models. This could include assessing biodistribution and editing efficiency in non-hepatic tissues.
  • ● Your work will contribute to the development of next-generation delivery technologies for CRISPR-based medicines. By identifying and characterizing VLPs with improved non-hepatic tropism, the project may help address an important challenge in the field and support the development of future genetic medicines for diseases affecting tissues beyond the liver.
  • ● This is an on-site position at AstraZeneca Gothenburg.
  • ● AstraZeneca does not support with accommodations for this role
  • ● Duration: Spring 2027

Requirements

  • ● Enrolled in a master's program in molecular biology, biotechnology, biomedicine, bioengineering, or a related field.
  • ● Hands-on experience with standard molecular and cell biology techniques, such as mammalian cell culture, transfection, PCR, and Western blot.
  • ● Prior exposure to viral vectors, VLPs, LNPs, or other delivery systems is a plus.
  • ● Familiarity with CRISPR/Cas systems is preferred but not required.
  • ● Ability to work independently and plan and execute experiments in a structured manner.
  • ● Ability to document experiments rigorously and communicate scientific results clearly in English.
  • ● So, what's next
  • ● Apply today and take the chance to be part of making a difference, making connections, and gaining the tools and experience to open doors and fulfil your potential. We can t wait to hear from you
  • ● We welcome your application as soon as possible, but ahead of the scheduled closing date October, 23 2026. In the event that we identify suitable candidates ahead of the scheduled closing date, we reserve the right to withdraw the vacancy earlier than published.
  • ● Date Posted 02-okt.-2026
  • ● Closing Date 23-okt.-2026